The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

A novel technology combined with optical tweezer C-trap technology gives researchers new insight into DNA repair mechanisms. Researchers at the University of Pittsburgh (PA, USA) have developed a ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and ...

You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...

The CRISPR gene editing technique has had a dramatic influence on biomedical research, and has even been applied to a few ...

Unlike most cell types, which continuously divide, neurons have to last for the life of the organism. How do they do that? One way neurons stay healthy is by repairing their DNA as they transcribe it.

The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...